Host: | E. coli |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Recombinant-Human SMTNL1-N-His-SUMO protein was developed from e. coli and has a target region of N-His-SUMO. For use in research applications. |
Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Gene Symbol: | SMTNL1 |
Gene ID: | 219537 |
Uniprot ID: | SMTL1_HUMAN |
Immunogen Region: | Lys371-Lys494 |
Immunogen: | Homo sapiens (Human) |
Post Translational Modifications | Maximal phosphorylation of Ser-336 correlates with maximal relaxation of aorta in response to acetylcholine. |
Function | Plays a role in the regulation of contractile properties of both striated and smooth muscles. When unphosphorylated, may inhibit myosin dephosphorylation. Phosphorylation at Ser-299 reduces this inhibitory activity. |
Protein Name | Smoothelin-Like Protein 1 |
Cellular Localisation | CytoplasmMyofibrilSarcomereI BandM LineNucleusColocalizes With Myh2In Its Unphosphorylated StateLocalizes To The CytoplasmPhosphorylation At Ser-301 Promotes Translocation To The Nucleus |
Alternative Protein Names | Smoothelin-Like Protein 1 proteinSMTNL1 protein |
Information sourced from Uniprot.org