Tissue Specificity | Predominantly expressed in adult forebrain. Expressed in fetal brain, lung and kidney. |
Post Translational Modifications | |
Function | Thought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors. During neural development involved in axonal navigation at the ventral midline of the neural tube and projection of axons to different regions. SLIT1 and SLIT2 together seem to be essential for midline guidance in the forebrain by acting as repulsive signal preventing inappropriate midline crossing by axons projecting from the olfactory bulb. |
Protein Name | Slit Homolog 1 ProteinSlit-1Multiple Epidermal Growth Factor-Like Domains Protein 4Multiple Egf-Like Domains Protein 4 |
Database Links | Reactome: R-HSA-373752Reactome: R-HSA-376176Reactome: R-HSA-428542Reactome: R-HSA-8985801Reactome: R-HSA-9010553 |
Cellular Localisation | Secreted |
Alternative ELISA Names | Slit Homolog 1 Protein ELISA kitSlit-1 ELISA kitMultiple Epidermal Growth Factor-Like Domains Protein 4 ELISA kitMultiple Egf-Like Domains Protein 4 ELISA kitSLIT1 ELISA kitKIAA0813 ELISA kitMEGF4 ELISA kitSLIL1 ELISA kit |
output | |
Information sourced from Uniprot.org