Function | Acetyl-CoA transporter that mediates active acetyl-CoA import through the endoplasmic reticulum (ER) membrane into the ER lumen where specific ER-based acetyl-CoA:lysine acetyltransferases are responsible for the acetylation of ER-based protein substrates, such as BACE1. Necessary for O-acetylation of gangliosides. |
Protein Name | Acetyl-Coenzyme A Transporter 1At-1Acetyl-Coa Transporter 1Solute Carrier Family 33 Member 1 |
Database Links | Reactome: R-HSA-425397Reactome: R-HSA-5619061 |
Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
Alternative Protein Names | Acetyl-Coenzyme A Transporter 1 proteinAt-1 proteinAcetyl-Coa Transporter 1 proteinSolute Carrier Family 33 Member 1 proteinSLC33A1 proteinACATN proteinAT1 protein |
Information sourced from Uniprot.org