Human SLC2A5 protein (Recombinant) (N-His-SUMO) (STJP007905)

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STJP007905
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Covered by St John's Laboratory Guarantee

Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human SLC2A5-N-His-SUMO protein was developed from e. coli and has a target region of N-His-SUMO. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: SLC2A5
Gene ID: 6518
Uniprot ID: GTR5_HUMAN
Immunogen Region: Pro461-Gln501
Immunogen: Homo sapiens (Human)
Function Functions as a fructose transporter that has only low activity with other monosaccharides. Can mediate the uptake of 2-deoxyglucose, but with low efficiency. Essential for fructose uptake in the small intestine. Plays a role in the regulation of salt uptake and blood pressure in response to dietary fructose. Required for the development of high blood pressure in response to high dietary fructose intake.
Protein Name Solute Carrier Family 2 - Facilitated Glucose Transporter Member 5
Fructose Transporter
Glucose Transporter Type 5 - Small Intestine
Glut-5
Database Links Reactome: R-HSA-6798695
Reactome: R-HSA-8981373
Cellular Localisation Apical Cell Membrane
Multi-Pass Membrane Protein
Cell Membrane
Sarcolemma
Localized On The Apical Membrane Of Jejunum Villi
But Also On Lateral Plasma Membranes Of The Villi
Transport To The Cell Membrane Is Dependent On Rab11a
Alternative Protein Names Solute Carrier Family 2 - Facilitated Glucose Transporter Member 5 protein
Fructose Transporter protein
Glucose Transporter Type 5 - Small Intestine protein
Glut-5 protein
SLC2A5 protein
GLUT5 protein

Information sourced from Uniprot.org

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