| Function | Mitochondrial electroneutral antiporter that exports citrate from the mitochondria into the cytosol in exchange for malate. Also able to mediate the exchange of citrate for isocitrate, phosphoenolpyruvate, cis-aconitate and to a lesser extent trans-aconitate, maleate and succinate. In the cytoplasm, citrate plays important roles in fatty acid and sterol synthesis, regulation of glycolysis, protein acetylation, and other physiopathological processes. |
| Protein Name | Tricarboxylate Transport Protein - MitochondrialCitrate Transport ProteinCtpMitochondrial Citrate CarrierCicSolute Carrier Family 25 Member 1Tricarboxylate Carrier Protein |
| Database Links | Reactome: R-HSA-428643 |
| Cellular Localisation | Mitochondrion Inner MembraneMulti-Pass Membrane Protein |
| Alternative Protein Names | Tricarboxylate Transport Protein - Mitochondrial proteinCitrate Transport Protein proteinCtp proteinMitochondrial Citrate Carrier proteinCic proteinSolute Carrier Family 25 Member 1 proteinTricarboxylate Carrier Protein proteinSLC25A1 proteinSLC20A3 protein |
Information sourced from Uniprot.org