| Short Description : | Recombinant-Human SLA-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications: | ELISA/Immunogen/SDS-PAGE/WB |
| Host: | E.coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Dilution Range: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin: | Please contact us for further information. |
| Gene Symbol: | SLA |
| Gene ID: | 6503 |
| Uniprot ID: | SLAP1_HUMAN |
| Immunogen: | Homo sapiens (Human) |
| Immunogen Region: | Ser24-Thr172 |
| Function | Adapter protein, which negatively regulates T-cell receptor (TCR) signaling. Inhibits T-cell antigen-receptor induced activation of nuclear factor of activated T-cells. Involved in the negative regulation of positive selection and mitosis of T-cells. May act by linking signaling proteins such as ZAP70 with CBL, leading to a CBL dependent degradation of signaling proteins. |
| Protein Name | Src-Like-AdapterSrc-Like-Adapter Protein 1Slap-1Hslap |
| Database Links | Reactome: R-HSA-9706369 |
| Cellular Localisation | CytoplasmEndosomeColocalizes With Endosomes |
| Alternative Protein Names | Src-Like-Adapter proteinSrc-Like-Adapter Protein 1 proteinSlap-1 proteinHslap proteinSLA proteinSLAP proteinSLAP1 protein |
Information sourced from Uniprot.org