| Host: | E. coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human SIVA1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | SIVA1 |
| Gene ID: | 10572 |
| Uniprot ID: | SIVA_HUMAN |
| Immunogen Region: | Met1-Thr175 |
| Immunogen: | Homo sapiens (Human) |
| Post Translational Modifications | Phosphorylated by ABL2/ARG in response to oxidative stress. |
| Function | Induces CD27-mediated apoptosis. Inhibits BCL2L1 isoform Bcl-x(L) anti-apoptotic activity. Inhibits activation of NF-kappa-B and promotes T-cell receptor-mediated apoptosis. |
| Protein Name | Apoptosis Regulatory Protein SivaCd27-Binding ProteinCd27bp |
| Cellular Localisation | CytoplasmNucleusIn The NucleusAccumulates In Dot-Like Structures |
| Alternative Protein Names | Apoptosis Regulatory Protein Siva proteinCd27-Binding Protein proteinCd27bp proteinSIVA1 proteinSIVA protein |
Information sourced from Uniprot.org