Human SIRPg (Signal Regulatory Protein Gamma) Sandwich ELISA Kit Ready-To-Use Kit (STJE0018555)
SPECIFICATIONS
General Information
| Short Description | This SIRPg Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates, cell lysates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 0.057ng/mL |
| Detection Limit | 0.156-10ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 3 hrs |
Target Information
| Gene Symbol | SIRPG |
| Gene ID | 55423 |
| Uniprot ID | SIRPG_HUMAN |
| Immunogen Region | Ready-To-Use |
| Sample Type | tissue homogenates, cell lysates or other biological fluids. |
Additional Info
| Tissue Specificity | Detected in liver, and at very low levels in brain, heart, lung, pancreas, kidney, placenta and skeletal muscle. Expressed on CD4+ T-cells, CD8+ T-cells, CD56-bright natural killer (NK) cells, CD20+ cells, and all activated NK cells. Mainly present in the paracortical T-cell area of lymph nodes, with only sparse positive cells in the mantle and in the germinal center of B-cell follicles. In the thymus, primarily expressed in the medulla on mature T-lymphocytes that have undergone thymic selection. |
| Post Translational Modifications | |
| Function | Probable immunoglobulin-like cell surface receptor. On binding with CD47, mediates cell-cell adhesion. Engagement on T-cells by CD47 on antigen-presenting cells results in enhanced antigen-specific T-cell proliferation and costimulates T-cell activation. |
| Protein Name | Signal-Regulatory Protein GammaSirp-GammaCd172 Antigen-Like Family Member BSignal-Regulatory Protein Beta-2Sirp-B2Sirp-Beta-2Cd Antigen Cd172g |
| Database Links | Reactome: R-HSA-202733Reactome: R-HSA-391160 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative ELISA Names | Signal-Regulatory Protein Gamma ELISA kitSirp-Gamma ELISA kitCd172 Antigen-Like Family Member B ELISA kitSignal-Regulatory Protein Beta-2 ELISA kitSirp-B2 ELISA kitSirp-Beta-2 ELISA kitCd Antigen Cd172g ELISA kitSIRPG ELISA kitSIRPB2 ELISA kit |
| output |
Information sourced from Uniprot.org