Tissue Specificity | Detected in monocytes and dendritic cells. |
Post Translational Modifications | N-glycosylated. |
Function | Immunoglobulin-like cell surface receptor involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. Participates also in the recruitment of tyrosine kinase SYK. Triggers activation of myeloid cells when associated with TYROBP. |
Protein Name | Signal-Regulatory Protein Beta-1Sirp-Beta-1Cd172 Antigen-Like Family Member BCd Antigen Cd172b |
Database Links | Reactome: R-HSA-2172127Reactome: R-HSA-391160Reactome: R-HSA-6798695 |
Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
Alternative ELISA Names | Signal-Regulatory Protein Beta-1 ELISA kitSirp-Beta-1 ELISA kitCd172 Antigen-Like Family Member B ELISA kitCd Antigen Cd172b ELISA kitSIRPB1 ELISA kit |
output | |
Information sourced from Uniprot.org