Human SIGLEC15/CD33L3 protein (Recombinant-Active) (C-His) (STJP012176)
SPECIFICATIONS
HostMammalian Cells
ConjugationUnconjugated
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Active-Human SIGLEC15/CD33L3-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications. |
| Applications | ELISA/WB |
| Host | Mammalian Cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Dilution Range | Reconstitute in sterile water for a stock solution. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | <0.1 EU/Mu g of the protein by the LAL method. |
| Immunoreactivity | Measured by its ability to inhibit anti-CD3 antibody induced IL-2 or IFN-gamma secretion by human T cells. The ED50 for this effect is 1-10 Mu g/mL. |
Target Information
| Gene Symbol | SIGLEC15 |
| Gene ID | 284266 |
| Uniprot ID | SIG15_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Phe20-Thr263 |
Additional Info
| Function | Binds sialylated glycoproteins. |
| Protein Name | Sialic Acid-Binding Ig-Like Lectin 15Siglec-15Cd33 Antigen-Like 3 |
| Database Links | Reactome: R-HSA-2172127 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Sialic Acid-Binding Ig-Like Lectin 15 proteinSiglec-15 proteinCd33 Antigen-Like 3 proteinSIGLEC15 proteinCD33L3 protein |
Information sourced from Uniprot.org