Post Translational Modifications | Phosphorylated on tyrosine residues. |
Function | Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,8-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. |
Protein Name | Sialic Acid-Binding Ig-Like Lectin 11Sialic Acid-Binding Lectin 11Siglec-11 |
Database Links | Reactome: R-HSA-198933 |
Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
Alternative Protein Names | Sialic Acid-Binding Ig-Like Lectin 11 proteinSialic Acid-Binding Lectin 11 proteinSiglec-11 proteinSIGLEC11 proteinUNQ9222 proteinPRO28718 protein |
Information sourced from Uniprot.org