Human Siglec-5/CD170 protein (Recombinant) (C-hFc&His) (STJP001207)
SPECIFICATIONS
HostHEK293 cells
ConjugationUnconjugated
ImmunogenRecombinant Human Siglec-5/CD170 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Glu17-Thr434) of human Siglec-5/CD170 (Accession #NP_003821.1) fused with a Fc, 6×His tag at the C-terminus.
General Information
| Short Description | Recombinant-Human Siglec-5/CD170-C-hFc&His protein was developed in hek293 cells using the region Glu17-Thr434. For use in research applications. |
| Host | HEK293 cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Formulation | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method | < 1.0 EU/Mu g of the protein by LAL method. |
Target Information
| Gene Symbol | SIGLEC5 |
| Gene ID | 8778 |
| Uniprot ID | SIGL5_HUMAN |
| Immunogen | Recombinant Human Siglec-5/CD170 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Glu17-Thr434) of human Siglec-5/CD170 (Accession #NP_003821.1) fused with a Fc, 6×His tag at the C-terminus. |
| Immunogen Region | Glu17-Thr434 |
| Immunogen Sequence | EKPVYELQVQKSVTVQEGLC VLVPCSFSYPWRSWYSSPPL YVYWFRDGEIPYYAEVVATN NPDRRVKPETQGRFRLLGDV QKKNCSLSIGDARMEDTGSY FFRVERGRDVKYSYQQNKLN LEVTALIEKPDIHFLEPLES GRPTRLSCSLPGSCEAGPPL TFSWTGNALSPLDPETTRSS ELTLTPRPEDHGTNLTCQMK RQGAQVTTERTVQLNVSYAP QTITIFRNGIALEILQNTS |
Additional Info
| Function | Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds equally to alpha-2,3-linked and alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. |
| Protein Name | Sialic Acid-Binding Ig-Like Lectin 5Siglec-5Cd33 Antigen-Like 2Obesity-Binding Protein 2Ob-Bp2Ob-Binding Protein 2Cd Antigen Cd170 |
| Database Links | Reactome: R-HSA-198933Reactome: R-HSA-6798695 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Sialic Acid-Binding Ig-Like Lectin 5 proteinSiglec-5 proteinCd33 Antigen-Like 2 proteinObesity-Binding Protein 2 proteinOb-Bp2 proteinOb-Binding Protein 2 proteinCd Antigen Cd170 proteinSIGLEC5 proteinCD33L2 proteinOBBP2 protein |
Information sourced from Uniprot.org