| Host: |
HEK293 cells |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Formulation: |
Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: |
< 1.0 EU/Mu g of the protein by LAL method. |
| Gene Symbol: |
SIGLEC5 |
| Gene ID: |
8778 |
| Uniprot ID: |
SIGL5_HUMAN |
| Immunogen: |
Recombinant Human Siglec-5/CD170 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Glu17-Thr434) of human Siglec-5/CD170 (Accession #NP_003821.1) fused with a Fc, 6×His tag at the C-terminus. |
| Immunogen Sequence: |
EKPVYELQVQKSVTVQEGLC VLVPCSFSYPWRSWYSSPPL YVYWFRDGEIPYYAEVVATN NPDRRVKPETQGRFRLLGDV QKKNCSLSIGDARMEDTGSY FFRVERGRDVKYSYQQNKLN LEVTALIEKPDIHFLEPLES GRPTRLSCSLPGSCEAGPPL TFSWTGNALSPLDPETTRSS ELTLTPRPEDHGTNLTCQMK RQGAQVTTERTVQLNVSYAP QTITIFRNGIALEILQNTS |
| Function | Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds equally to alpha-2,3-linked and alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. |
| Protein Name | Sialic Acid-Binding Ig-Like Lectin 5Siglec-5Cd33 Antigen-Like 2Obesity-Binding Protein 2Ob-Bp2Ob-Binding Protein 2Cd Antigen Cd170 |
| Database Links | Reactome: R-HSA-198933Reactome: R-HSA-6798695 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Sialic Acid-Binding Ig-Like Lectin 5 proteinSiglec-5 proteinCd33 Antigen-Like 2 proteinObesity-Binding Protein 2 proteinOb-Bp2 proteinOb-Binding Protein 2 proteinCd Antigen Cd170 proteinSIGLEC5 proteinCD33L2 proteinOBBP2 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
