| Host: |
HEK293 cells |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Formulation: |
Lyophilised from a 0.22 Mu m filtered solution of PBS, 300mM NaCl, pH 7.4. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: |
< 0.1 EU/Mu g of the protein by LAL method. |
| Immunoreactivity: |
Measured by its ability to inhibit Anti-CD3-induced proliferation of jurkat cells. The ED50 for this effect is 1.8-7.2 Mu g/mL. |
| Gene Symbol: |
SIGLEC15 |
| Gene ID: |
284266 |
| Uniprot ID: |
SIG15_HUMAN |
| Immunogen Region: |
Phe20-Thr263 |
| Immunogen: |
Recombinant Human Siglec-15/CD33L3 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Phe20-Thr263) of human Siglec-15/CD33L3 (Accession #NP_998767.1) fused with a Fc, 6×His tag at the C-terminus. |
| Immunogen Sequence: |
FVRTKIDTTENLLNTEVHSS PAQRWSMQVPPEVSAEAGDA AVLPCTFTHPHRHYDGPLTA IWRAGEPYAGPQVFRCAAAR GSELCQTALSLHGRFRLLGN PRRNDLSLRVERLALADDRR YFCRVEFAGDVHDRYESRHG VRLHVTAAPRIVNISVLPSP AHAFRALCTAEGEPPPALAW SGPALGNSLAAVRSPREGHG HLVTAELPALTHDGRYTCTA ANSLGRSEASVYLFRFHGA |
| Function | Binds sialylated glycoproteins. |
| Protein Name | Sialic Acid-Binding Ig-Like Lectin 15Siglec-15Cd33 Antigen-Like 3 |
| Database Links | Reactome: R-HSA-2172127 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Sialic Acid-Binding Ig-Like Lectin 15 proteinSiglec-15 proteinCd33 Antigen-Like 3 proteinSIGLEC15 proteinCD33L3 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
