Human Siglec-15/CD33L3 protein (Recombinant) (C-hFc & His) (STJP002727)

SKU:
STJP002727

Current Stock:
Host: HEK293 cells
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human Siglec-15/CD33L3-C-hFc & His protein was developed from hek293 cells and has a target region of C-hFc & His. For use in research applications.
Formulation: Lyophilized from a 0.22 Mu m filtered solution of PBS, 300mM NaCl, pH 7.4.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Immunoreactivity: Measured by its ability to inhibit Anti-CD3-induced proliferation of jurkat cells. The ED50 for this effect is 1.8-7.2 Mu g/mL.
Gene Symbol: SIGLEC15
Gene ID: 284266
Uniprot ID: SIG15_HUMAN
Immunogen Region: Phe20-Thr263
Immunogen: Recombinant Human Siglec-15/CD33L3 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Phe20-Thr263) of human Siglec-15/CD33L3 (Accession #NP_998767.1) fused with a Fc, 6×His tag at the C-terminus.
Function Binds sialylated glycoproteins.
Protein Name Sialic Acid-Binding Ig-Like Lectin 15
Siglec-15
Cd33 Antigen-Like 3
Database Links Reactome: R-HSA-2172127
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Sialic Acid-Binding Ig-Like Lectin 15 protein
Siglec-15 protein
Cd33 Antigen-Like 3 protein
SIGLEC15 protein
CD33L3 protein

Information sourced from Uniprot.org

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