Human SGPP2 (Sphingosine-1-Phosphate Phosphatase 2) Ready-To-Use Sandwich ELISA Kit (STJE0018530)

Human SGPP2 (Sphingosine-1-Phosphate Phosphatase 2) Ready-To-Use Sandwich ELISA Kit (STJE0018530)

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STJE0018530
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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.059ng/mL
Detection Limit: 0.156-10ng/mL
Short Description : This SGPP2 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates or other biological fluids.
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: SGPP2
Gene ID: 130367
Uniprot ID: SGPP2_HUMAN
Immunogen Region: Ready-To-Use
Sample Type: tissue homogenates or other biological fluids.
Tissue Specificity Expressed strongly in kidney and heart, followed by brain, colon, small intestine and lung. Not detected in skeletal muscle, thymus, spleen, liver, placenta, and peripheral blood leukocytes.
Post Translational Modifications
Function Has specific phosphohydrolase activity towards sphingoid base 1-phosphates. Has high phosphohydrolase activity against dihydrosphingosine-1-phosphate and sphingosine-1-phosphate (S1P) in vitro. Sphingosine-1-phosphate phosphatase activity is needed for efficient recycling of sphingosine into the sphingolipid synthesis pathway. May play a role in attenuating intracellular sphingosine 1-phosphate (S1P) signaling. May play a role in pro-inflammatory signaling. Plays a role in the regulation of pancreatic islet beta-cell endoplasmic reticulum stress and proliferation.
Protein Name Sphingosine-1-Phosphate Phosphatase 2
Sppase2
Spp2
Hspp2
Sphingosine-1-Phosphatase 2
Database Links Reactome: R-HSA-9845614
Cellular Localisation Endoplasmic Reticulum Membrane
Multi-Pass Membrane Protein
Alternative ELISA Names Sphingosine-1-Phosphate Phosphatase 2 ELISA kit
Sppase2 ELISA kit
Spp2 ELISA kit
Hspp2 ELISA kit
Sphingosine-1-Phosphatase 2 ELISA kit
SGPP2 ELISA kit
output

Information sourced from Uniprot.org

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