Human SGPP2 protein (Recombinant) (N-His-KSI) (STJP011023)

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STJP011023
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Covered by St John's Laboratory Guarantee

Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human SGPP2-N-His-KSI protein was developed from e. coli and has a target region of N-His-KSI. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: SGPP2
Gene ID: 130367
Uniprot ID: SGPP2_HUMAN
Immunogen Region: Ala2-Tyr87
Immunogen: Homo sapiens (Human)
Function Has specific phosphohydrolase activity towards sphingoid base 1-phosphates. Has high phosphohydrolase activity against dihydrosphingosine-1-phosphate and sphingosine-1-phosphate (S1P) in vitro. Sphingosine-1-phosphate phosphatase activity is needed for efficient recycling of sphingosine into the sphingolipid synthesis pathway. May play a role in attenuating intracellular sphingosine 1-phosphate (S1P) signaling. May play a role in pro-inflammatory signaling. Plays a role in the regulation of pancreatic islet beta-cell endoplasmic reticulum stress and proliferation.
Protein Name Sphingosine-1-Phosphate Phosphatase 2
Sppase2
Spp2
Hspp2
Sphingosine-1-Phosphatase 2
Database Links Reactome: R-HSA-9845614
Cellular Localisation Endoplasmic Reticulum Membrane
Multi-Pass Membrane Protein
Alternative Protein Names Sphingosine-1-Phosphate Phosphatase 2 protein
Sppase2 protein
Spp2 protein
Hspp2 protein
Sphingosine-1-Phosphatase 2 protein
SGPP2 protein

Information sourced from Uniprot.org

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