| Tissue Specificity | Highly expressed in tissues with high one-carbon metabolism activity, such as blood, liver and kidney. |
| Post Translational Modifications | |
| Function | Amino acid transporter importing serine, an essential substrate of the mitochondrial branch of the one-carbon pathway, into mitochondria. Mitochondrial serine is then converted to glycine and formate, which exits to the cytosol where it is used to generate the charged folates that serve as one-carbon donors. May also transport other amino acids including alanine and cysteine. |
| Protein Name | Sideroflexin-1 |
| Database Links | |
| Cellular Localisation | Mitochondrion Inner MembraneMulti-Pass Membrane Protein |
| Alternative ELISA Names | Sideroflexin-1 ELISA kitSFXN1 ELISA kit |
| output | |
Information sourced from Uniprot.org
