Post Translational Modifications | Proteolytically cleaved at Pro-39 by both the prolyl endopeptidase FAP form and antiplasmin-cleaving enzyme FAP soluble form to generate mature alpha-2-antiplasmin. |
Function | Serine protease inhibitor. The major targets of this inhibitor are plasmin and trypsin, but it also inactivates matriptase-3/TMPRSS7 and chymotrypsin. |
Protein Name | Alpha-2-AntiplasminAlpha-2-ApAlpha-2-Plasmin InhibitorAlpha-2-PiSerpin F2 |
Database Links | Reactome: R-HSA-114608Reactome: R-HSA-75205 |
Cellular Localisation | Secreted |
Alternative Protein Names | Alpha-2-Antiplasmin proteinAlpha-2-Ap proteinAlpha-2-Plasmin Inhibitor proteinAlpha-2-Pi proteinSerpin F2 proteinSERPINF2 proteinAAP proteinPLI protein |
Information sourced from Uniprot.org