Function | May be involved in the regulation of serine proteinases present in the brain or extravasated from the blood. Inhibitor of cathepsin G, kallikrein-8 and thrombin. May play an important role in the inner ear in the protection against leakage of lysosomal content during stress and loss of this protection results in cell death and sensorineural hearing loss. |
Protein Name | Serpin B6Cytoplasmic AntiproteinaseCapPeptidase Inhibitor 6Pi-6Placental Thrombin Inhibitor |
Database Links | Reactome: R-HSA-6798695Reactome: R-HSA-75205 |
Cellular Localisation | Cytoplasm |
Alternative Protein Names | Serpin B6 proteinCytoplasmic Antiproteinase proteinCap proteinPeptidase Inhibitor 6 proteinPi-6 proteinPlacental Thrombin Inhibitor proteinSERPINB6 proteinPI6 proteinPTI protein |
Information sourced from Uniprot.org