| Short Description : | Recombinant-Human SERPINA4-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications. |
| Applications: | ELISA/WB |
| Host: | Mammalian Cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Conjugation: | Unconjugated |
| Dilution Range: | Reconstitute in sterile water for a stock solution. |
| Formulation: | Lyophilized from a 0.22 Mu m filtered solution in 20mM PB, 6% Trehalose, 4% Mannitol, 50mM NaCl, 0.05% Tween 80, pH 6.0. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin: | < 1 EU/µg as determined by LAL test. |
| Gene Symbol: | SERPINA4 |
| Gene ID: | 5267 |
| Uniprot ID: | KAIN_HUMAN |
| Immunogen: | Homo sapiens (Human) |
| Immunogen Region: | Gln21-Pro427 |
| Post Translational Modifications | The N-terminus is blocked. |
| Function | Inhibits human amidolytic and kininogenase activities of tissue kallikrein. Inhibition is achieved by formation of an equimolar, heat- and SDS-stable complex between the inhibitor and the enzyme, and generation of a small C-terminal fragment of the inhibitor due to cleavage at the reactive site by tissue kallikrein. |
| Protein Name | KallistatinKallikrein InhibitorPeptidase Inhibitor 4Pi-4Serpin A4 |
| Database Links | Reactome: R-HSA-114608Reactome: R-HSA-9925561 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Kallistatin proteinKallikrein Inhibitor proteinPeptidase Inhibitor 4 proteinPi-4 proteinSerpin A4 proteinSERPINA4 proteinKST proteinPI4 protein |
Information sourced from Uniprot.org