| Host: | E.coli |
| Applications: | SDS-PAGE |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human Serpin A12/Vaspin-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Formulation: | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.2mM PMSF, 10% Glycerol |
| Concentration: | 1 mg/mL |
| Storage Instruction: | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Endotoxin: | < 1 EU per 1ug of protein (determined by LAL method) |
| Gene Symbol: | SERPINA12 |
| Gene ID: | 145264 |
| Uniprot ID: | SPA12_HUMAN |
| Immunogen Region: | 21-414aa |
| Accession Number: | NP_776249.1 |
| Immunogen: | Human |
| Immunogen Sequence: |
| Tissue Specificity | Expressed in visceral adipose tissues. |
| Post Translational Modifications | Glycosylation slightly decreases affinity for heparin, but otherwise has no significant effect on KLK7 inhibitory activity or thermal stability of the protein. |
| Function | Adipokine that modulates insulin action by specifically inhibiting its target protease KLK7 in white adipose tissues. |
| Protein Name | Serpin A12Ol-64Visceral Adipose Tissue-Derived Serine Protease InhibitorVaspinVisceral Adipose-Specific Serpin |
| Database Links | |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Serpin A12 proteinOl-64 proteinVisceral Adipose Tissue-Derived Serine Protease Inhibitor proteinVaspin proteinVisceral Adipose-Specific Serpin proteinSERPINA12 protein |
Information sourced from Uniprot.org