Human SEPTIN8 protein (Recombinant) (N-His) (STJP007795)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human SEPTIN8-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | SEPTIN8 |
| Gene ID | 23176 |
| Uniprot ID | SEPT8_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Gly26-Gly309 |
Additional Info
| Function | Filament-forming cytoskeletal GTPase. May play a role in platelet secretion. Seems to participate in the process of SNARE complex formation in synaptic vesicles. Isoform 4: Stabilizes BACE1 protein levels and promotes the sorting and accumulation of BACE1 to the recycling or endosomal compartments, modulating the beta-amyloidogenic processing of APP. |
| Protein Name | Septin-8 |
| Database Links | |
| Cellular Localisation | CytoplasmCytoskeletonSynapseCell ProjectionAxonCytoplasmic VesicleSecretory VesicleSynaptic Vesicle MembranePresynapseExpressed In Axons Of Immature NeuronsLocalizes To Synapses In Mature NeuronsIn PlateletsFound In Areas Surrounding Alpha-Granules |
| Alternative Protein Names | Septin-8 proteinSEPTIN8 proteinKIAA0202 proteinSEPT8 protein |
Information sourced from Uniprot.org