Human SEPTIN6 protein (Recombinant) (N-His) (STJP007666)

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STJP007666
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human SEPTIN6-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: SEPTIN6
Gene ID: 23157
Uniprot ID: SEPT6_HUMAN
Immunogen Region: Gly24-Gly307
Immunogen: Homo sapiens (Human)
Function Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Involved in cytokinesis. May play a role in HCV RNA replication. Forms a filamentous structure with SEPTIN12, SEPTIN6, SEPTIN2 and probably SEPTIN4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation.
Protein Name Septin-6
Cellular Localisation Cytoplasm
Cytoskeleton
Spindle
Chromosome
Centromere
Kinetochore
Cleavage Furrow
Midbody
Cell Projection
Cilium
Flagellum
In Metaphase Cells
Localized Within The Microtubule Spindle
At The Metaphase Plate
In Close Apposition To The Kinetochores Of The Congressed Chromosomes
In Cells Undergoing Cytokinesis
Localized To The Midbody
The Ingressing Cleavage Furrow
And The Central Spindle
Found In The Sperm Annulus
Alternative Protein Names Septin-6 protein
SEPTIN6 protein
KIAA0128 protein
SEP2 protein
SEPT6 protein

Information sourced from Uniprot.org

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