Human SEMG1 protein (Recombinant) (N-His) (STJP003671)

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STJP003671
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human SEMG1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: SEMG1
Gene ID: 6406
Uniprot ID: SEMG1_HUMAN
Immunogen Region: Gln24-Thr462
Immunogen: Homo sapiens (Human)
Post Translational Modifications Transglutaminase substrate. Rapidly cleaved after ejaculation by KLK3/PSA, resulting in liquefaction of the semen coagulum and the progressive release of motile spermatozoa.
Function Predominant protein in semen. It participates in the formation of a gel matrix entrapping the accessory gland secretions and ejaculated spermatozoa. Fragments of semenogelin and/or fragments of the related proteins may contribute to the activation of progressive sperm movements as the gel-forming proteins are fragmented by KLK3/PSA. Alpha-inhibin-92 and alpha-inhibin-31, derived from the proteolytic degradation of semenogelin, inhibit the secretion of pituitary follicle-stimulating hormone.
Protein Name Semenogelin-1
Cancer/Testis Antigen 103
Semenogelin I
Sgi Cleaved Into - Alpha-Inhibin-92 - Alpha-Inhibin-31 - Seminal Basic Protein
Database Links Reactome: R-HSA-6803157
Reactome: R-HSA-977225
Cellular Localisation Secreted
Alternative Protein Names Semenogelin-1 protein
Cancer/Testis Antigen 103 protein
Semenogelin I protein
Sgi Cleaved Into - Alpha-Inhibin-92 - Alpha-Inhibin-31 - Seminal Basic Protein protein
SEMG1 protein
SEMG protein

Information sourced from Uniprot.org

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