Human SEMA5A (Semaphorin 5A) Sandwich ELISA Kit Ready-To-Use Kit (STJE0018481)

Name: Human SEMA5A (Semaphorin 5A) Sandwich ELISA Kit Ready-To-Use Kit (STJE0018481)
SKU: STJE0018481
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⇓ Datasheet ⇓ SDS

SPECIFICATIONS

STJE0018481

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Short Description	This SEMA5A Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates or other biological fluids..
Applications	ELISA
Reactivity	Human
Sensitivity	0.27ng/mL
Detection Limit	0.781-50ng/mL
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Storage Instruction	The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time	3 hrs

Gene Symbol	SEMA5A
Gene ID	9037
Uniprot ID	SEM5A_HUMAN
Immunogen Region	Ready-To-Use
Sample Type	tissue homogenates or other biological fluids.

Tissue Specificity
Post Translational Modifications
Function	Bifunctional axonal guidance cue regulated by sulfated proteoglycans.attractive effects result from interactions with heparan sulfate proteoglycans (HSPGs), while the inhibitory effects depend on interactions with chondroitin sulfate proteoglycans (CSPGs). Ligand for receptor PLXNB3. In glioma cells, SEMA5A stimulation of PLXNB3 results in the disassembly of F-actin stress fibers, disruption of focal adhesions and cellular collapse as well as inhibition of cell migration and invasion through ARHGDIA-mediated inactivation of RAC1. May promote angiogenesis by increasing endothelial cell proliferation and migration and inhibiting apoptosis.
Protein Name	Semaphorin-5a Semaphorin-F Sema F
Database Links	Reactome: R-HSA-416700 Reactome: R-HSA-5083635 Reactome: R-HSA-5173214
Cellular Localisation	Membrane Single-Pass Type I Membrane Protein
Alternative ELISA Names	Semaphorin-5a ELISA kit Semaphorin-F ELISA kit Sema F ELISA kit SEMA5A ELISA kit SEMAF ELISA kit
output

Information sourced from Uniprot.org