Human SEC22B protein (Recombinant) (His-Tag) (STJP017818)

SPECIFICATIONS
HostE.coli
ImmunogenHuman
STJP017818
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General Information

Short DescriptionRecombinant-Human SEC22B-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
ApplicationsSDS-PAGE/Denatured
HostE.coli
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Concentration0.5 mg/mL
FormulationLiquid in 20mM Tris-HCl buffer (pH 8.0) containing 2M urea, 10% Glycerol, 0.15M NaCl
Storage InstructionFor short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolSEC22B
Gene ID9554
Uniprot IDSC22B_HUMAN
Accession NumberNP_004883
ImmunogenHuman
Immunogen Region14-194aa
Immunogen SequenceLPLAAS MQEDEQSGRD LQQYQSQAKQ LFRKLNEQSP TRCTLEAGAM TFHYIIEQGV CYLVLCEAAF PKKLAFAYLE DLHSEFDEQH GKKVPTVSRP YSFIEFDTFI QKTKKLYIDS RARRNLGSIN TELQDVQRIM VANIEEVLQR GEALSALDSK ANNLSSLSKK YRQDAKYLNM RSTYA

Additional Info

Function SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER.
Protein Name Vesicle-Trafficking Protein Sec22b
Er-Golgi Snare Of 24 Kda
Ers-24
Ers24
Sec22 Vesicle-Trafficking Protein Homolog B
Sec22 Vesicle-Trafficking Protein-Like 1
Database Links Reactome: R-HSA-1236974
Reactome: R-HSA-204005
Reactome: R-HSA-5694530
Reactome: R-HSA-6811434
Cellular Localisation Endoplasmic Reticulum Membrane
Single-Pass Type Iv Membrane Protein
Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
Golgi Apparatus
Cis-Golgi Network Membrane
Trans-Golgi Network Membrane
Melanosome
Concentrated Most In The Intermediate Compartment/Cis-Golgi Network And The Cis-Golgi Cisternae 1 And 2
Greatly Reduced In Concentration At The Trans End Of The Golgi Apparatus
Identified By Mass Spectrometry In Melanosome Fractions From Stage I To Stage Iv
Alternative Protein Names Vesicle-Trafficking Protein Sec22b protein
Er-Golgi Snare Of 24 Kda protein
Ers-24 protein
Ers24 protein
Sec22 Vesicle-Trafficking Protein Homolog B protein
Sec22 Vesicle-Trafficking Protein-Like 1 protein
SEC22B protein
SEC22L1 protein

Information sourced from Uniprot.org

Citations

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