| Short Description : | Recombinant-Human SDHAF2-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications: | SDS-PAGE |
| Host: | E.coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Concentration: | 0.5 mg/mL |
| Formulation: | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 30% Glycerol, 1mM DTT |
| Storage Instruction: | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SDHAF2 |
| Gene ID: | 54949 |
| Uniprot ID: | SDHF2_HUMAN |
| Accession Number: | NP_060311 |
| Immunogen: | Human |
| Immunogen Region: | 30-166aa |
| Immunogen Sequence: | MGSSHHHHHH SSGLVPRGSH MGSSFRRFYR GDSPTDSQKD MIEIPLPPWQ ERTDESIETK RARLLYESRK RGMLENCILL SLFAKEHLQH MTEKQLNLYD RLINEPSNDW DIYYWATEAK PAPEIFENEV MALLRDFAKN KNKEQRLRAP DLEYLFEKPR |
| Function | Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SDHA of the SDH catalytic dimer. |
| Protein Name | Succinate Dehydrogenase Assembly Factor 2 - MitochondrialSdh Assembly Factor 2Sdhaf2 |
| Database Links | Reactome: R-HSA-9854311 |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Protein Names | Succinate Dehydrogenase Assembly Factor 2 - Mitochondrial proteinSdh Assembly Factor 2 proteinSdhaf2 proteinSDHAF2 proteinC11orf79 proteinPGL2 proteinSDH5 protein |
Information sourced from Uniprot.org
