Human SDHA protein (Recombinant) (N-His) (STJP007350)

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STJP007350
£328.50 - £1,437.50
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human SDHA-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: SDHA
Gene ID: 6389
Uniprot ID: SDHA_HUMAN
Immunogen Region: Ser44-Tyr664
Immunogen: Homo sapiens (Human)
Function Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). SDH also oxidizes malate to the non-canonical enol form of oxaloacetate, enol-oxaloacetate. Enol-oxaloacetate, which is a potent inhibitor of the succinate dehydrogenase activity, is further isomerized into keto-oxaloacetate. Can act as a tumor suppressor.
Protein Name Succinate Dehydrogenase Ubiquinone Flavoprotein Subunit - Mitochondrial
Flavoprotein Subunit Of Complex Ii
Fp
Malate Dehydrogenase Quinone Flavoprotein Subunit
Database Links Reactome: R-HSA-611105
Reactome: R-HSA-71403
Reactome: R-HSA-9854311
Cellular Localisation Mitochondrion Inner Membrane
Peripheral Membrane Protein
Matrix Side
Alternative Protein Names Succinate Dehydrogenase Ubiquinone Flavoprotein Subunit - Mitochondrial protein
Flavoprotein Subunit Of Complex Ii protein
Fp protein
Malate Dehydrogenase Quinone Flavoprotein Subunit protein
SDHA protein
SDH2 protein
SDHF protein

Information sourced from Uniprot.org

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