Human SCO1 protein (Recombinant) (N-GST) (STJP014295)
SPECIFICATIONS
HostE.coli
ConjugationUnconjugated
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human SCO1-N-GST protein was developed from e.coli and has a target region of N-GST. For use in research applications. |
| Applications | ELISA/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Dilution Range | Reconstitute in sterile water for a stock solution. |
| Formulation | Lyophilized from a 0.22 Mu m filtered solution in 50mM PB, 1mM DTT, pH 7.2. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8ยฐC for one week. Store at-20 to-80ยฐC for twelve months from the date of receipt. |
| Endotoxin | < 1 EU/ยตg as determined by LAL test. |
Target Information
| Gene Symbol | SCO1 |
| Gene ID | 6341 |
| Uniprot ID | SCO1_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Gly132-Ser301 |
Additional Info
| Function | Copper metallochaperone essential for the maturation of cytochrome c oxidase subunit II (MT-CO2/COX2). Not required for the synthesis of MT-CO2/COX2 but plays a crucial role in stabilizing MT-CO2/COX2 during its subsequent maturation. Involved in transporting copper to the Cu(A) site on MT-CO2/COX2. Plays an important role in the regulation of copper homeostasis by controlling the abundance and cell membrane localization of copper transporter CTR1. |
| Protein Name | Protein Sco1 Homolog - Mitochondrial |
| Database Links | Reactome: R-HSA-9864848 |
| Cellular Localisation | MitochondrionMitochondrion Inner MembraneSingle-Pass Membrane Protein |
| Alternative Protein Names | Protein Sco1 Homolog - Mitochondrial proteinSCO1 proteinSCOD1 protein |
Information sourced from Uniprot.org