| Function | Secreted cytokine-like protein. Binds to the scavenger receptor MARCO. Can also bind to pathogens including the Gram-positive bacterium L.monocytogenes, the Gram-negative bacterium P.aeruginosa, and yeast. Strongly inhibits phospholipase A2 (PLA2G1B) activity. Seems to have anti-inflammatory effects in respiratory epithelium. Also has anti-fibrotic activity in lung. May play a role in fetal lung development and maturation. Promotes branching morphogenesis during early stages of lung development. In the pituitary, may inhibit production of follicle-stimulating hormone (FSH) and luteinizing hormone (LH). |
| Protein Name | Secretoglobin Family 3a Member 2Pneumo Secretory Protein 1Pnsp-1Uteroglobin-Related Protein 1 |
| Database Links | Reactome: R-HSA-3000480 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Secretoglobin Family 3a Member 2 proteinPneumo Secretory Protein 1 proteinPnsp-1 proteinUteroglobin-Related Protein 1 proteinSCGB3A2 proteinPNSP1 proteinUGRP1 proteinUNQ566 proteinPRO1128 protein |
Information sourced from Uniprot.org