Human SCG3 protein (Recombinant) (N-His) (STJP006335)

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STJP006335
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human SCG3-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: SCG3
Gene ID: 29106
Uniprot ID: SCG3_HUMAN
Immunogen Region: Phe20-Leu468
Immunogen: Homo sapiens (Human)
Post Translational Modifications O-glycosylated.
Function Member of the granin protein family that regulates the biogenesis of secretory granules. Acts as a sorting receptor for intragranular proteins including chromogranin A/CHGA. May also play a role in angiogenesis. Promotes endothelial proliferation, migration and tube formation through MEK/ERK signaling pathway.
Protein Name Secretogranin-3
Secretogranin Iii
Sgiii
Database Links Reactome: R-HSA-114608
Reactome: R-HSA-381426
Reactome: R-HSA-8957275
Cellular Localisation Cytoplasmic Vesicle
Secretory Vesicle
Secretory Vesicle Membrane
Peripheral Membrane Protein
Secreted
Associated With The Secretory Granule Membrane Through Direct Binding To Cholesterol-Enriched Lipid Rafts
Alternative Protein Names Secretogranin-3 protein
Secretogranin Iii protein
Sgiii protein
SCG3 protein
UNQ2502 protein
PRO5990 protein

Information sourced from Uniprot.org

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