Tissue Specificity | Expressed at highest levels in colon and at moderate levels in thymus, kidney, liver, small intestine, and lung. Low expression in heart and no expression is seen in brain, skeletal muscle, spleen, placenta and peripheral blood leukocytes. |
Post Translational Modifications | |
Function | Modulates P53/TP53 protein levels, and thereby plays a role in the regulation of cell survival and apoptosis. Depending on the context, it can promote cell proliferation or apoptosis. Plays a role in the regulation of cell migration by modulating the levels of MMP2, a matrix protease that is under transcriptional control of P53/TP53. Does not bind calcium. |
Protein Name | Protein S100-A14S100 Calcium-Binding Protein A14S114 |
Database Links | |
Cellular Localisation | Cytoplasm |
Alternative ELISA Names | Protein S100-A14 ELISA kitS100 Calcium-Binding Protein A14 ELISA kitS114 ELISA kitS100A14 ELISA kitS100A15 ELISA kit |
output | |
Information sourced from Uniprot.org