Human RXRG protein (Recombinant) (N-His) (STJP004788)

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STJP004788
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human RXRG-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: RXRG
Gene ID: 6258
Uniprot ID: RXRG_HUMAN
Immunogen Region: Pro12-Ala220
Immunogen: Homo sapiens (Human)
Post Translational Modifications Acetylated by EP300.
Function Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. The high affinity ligand for RXRs is 9-cis retinoic acid.
Protein Name Retinoic Acid Receptor Rxr-Gamma
Nuclear Receptor Subfamily 2 Group B Member 3
Retinoid X Receptor Gamma
Database Links Reactome: R-HSA-383280
Reactome: R-HSA-5362517
Cellular Localisation Nucleus
Cytoplasm
Alternative Protein Names Retinoic Acid Receptor Rxr-Gamma protein
Nuclear Receptor Subfamily 2 Group B Member 3 protein
Retinoid X Receptor Gamma protein
RXRG protein
NR2B3 protein

Information sourced from Uniprot.org

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