Human RTN4RL1 protein (Recombinant) (C-His) (STJP013695)

SKU:
STJP013695-100
£503.50
Free Shipping
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Short Description :Recombinant-Human RTN4RL1-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications.
Applications:ELISA/WB
Host:Mammalian Cells
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Conjugation:Unconjugated
Dilution Range:Reconstitute in sterile water for a stock solution.
Formulation:Lyophilized from a 0.22 Mu m filtered solution in 20mM PB, 150mM NaCl, pH 7.4.
Storage Instruction:Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin:< 1 EU/µg as determined by LAL test.
Gene Symbol:RTN4RL1
Gene ID:146760
Uniprot ID:R4RL1_HUMAN
Immunogen:Homo sapiens (Human)
Immunogen Region:Cys25-Ala419
Function Cell surface receptor. Plays a functionally redundant role in postnatal brain development and in regulating axon regeneration in the adult central nervous system. Contributes to normal axon migration across the brain midline and normal formation of the corpus callosum. Protects motoneurons against apoptosis.protection against apoptosis is probably mediated by MAG. Plays a role in inhibiting neurite outgrowth and axon regeneration via its binding to neuronal chondroitin sulfate proteoglycans. Binds heparin. Like other family members, plays a role in restricting the number dendritic spines and the number of synapses that are formed during brain development. Signaling mediates activation of Rho and downstream reorganization of the actin cytoskeleton.
Protein Name Reticulon-4 Receptor-Like 1
Nogo Receptor-Like 2
Nogo-66 Receptor Homolog 2
Nogo-66 Receptor-Related Protein 3
Ngr3
Database Links Reactome: R-HSA-163125
Cellular Localisation Cell Membrane
Lipid-Anchor
Gpi-Anchor
Membrane Raft
Perikaryon
Cell Projection
Localized To The Surface Of Neurons
Including Axons
Alternative Protein Names Reticulon-4 Receptor-Like 1 protein
Nogo Receptor-Like 2 protein
Nogo-66 Receptor Homolog 2 protein
Nogo-66 Receptor-Related Protein 3 protein
Ngr3 protein
RTN4RL1 protein
NGRH2 protein
NGRL2 protein

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJP014314 Human APBA3 protein (Recombinant) (C-His) (STJP014314) E.coli ELISA/WB
STJP014380 Human ANXA6 protein (Recombinant) (C-His) (STJP014380) E.coli ELISA/WB
STJP014407 Human HSPA8 protein (Recombinant) (C-His) (STJP014407) E.coli ELISA/WB
STJP020292 Human DLK1 protein (Recombinant) (C-His) (STJP020292) HEK293 cells
STJP020068 Human TSLP protein (Recombinant) (C-His) (STJP020068) HEK293 cells

Related Products

!