| Host: | E. coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human RPL23A-N-His-SUMO protein was developed from e. coli and has a target region of N-His-SUMO. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | RPL23A |
| Gene ID: | 6147 |
| Uniprot ID: | RL23A_HUMAN |
| Immunogen Region: | Lys70-Ile156 |
| Immunogen: | Homo sapiens (Human) |
| Function | Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Binds a specific region on the 26S rRNA. May promote p53/TP53 degradation possibly through the stimulation of MDM2-mediated TP53 polyubiquitination. |
| Protein Name | Large Ribosomal Subunit Protein Ul2360s Ribosomal Protein L23a |
| Database Links | Reactome: R-HSA-156827Reactome: R-HSA-156902Reactome: R-HSA-1799339Reactome: R-HSA-192823Reactome: R-HSA-2408557Reactome: R-HSA-6791226Reactome: R-HSA-72689Reactome: R-HSA-72706Reactome: R-HSA-72764Reactome: R-HSA-9010553Reactome: R-HSA-9633012Reactome: R-HSA-975956Reactome: R-HSA-975957 |
| Cellular Localisation | CytoplasmNucleusAlthough Rpl23a Is Functional Within The CytoplasmThe Assembly Of Ribosomal Subunits Occurs In The NucleusRpl23a Nuclear Import Is Mediated By Ipo5/Ranbp5Ipo7/Ranbp7Kpnb1/Importin-Beta Or Tpno1/Trn |
| Alternative Protein Names | Large Ribosomal Subunit Protein Ul23 protein60s Ribosomal Protein L23a proteinRPL23A protein |
Information sourced from Uniprot.org