Host: |
HEK293 cells |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Formulation: |
Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Determination Method: |
<0.1 EU/Mu g |
Gene Symbol: |
ROBO4 |
Gene ID: |
54538 |
Uniprot ID: |
ROBO4_HUMAN |
Immunogen: |
Recombinant Human ROBO4 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gln28-Arg467) of human ROBO4/ECSM4 (Accession #NP_061928.4) fused with a Fc, 6×His tag at the C-terminus. |
Immunogen Sequence: |
QDSPPQILVHPQDQLFQGPG PARMSCQASGQPPPTIRWLL NGQPLSMVPPDPHHLLPDGT LLLLQPPARGHAHDGQALST DLGVYTCEASNRLGTAVSRG ARLSVAVLREDFQIQPRDMV AVVGEQFTLECGPPWGHPEP TVSWWKDGKPLALQPGRHTV SGGSLLMARAEKSDEGTYMC VATNSAGHRESRAARVSIQE PQDYTEPVELLAVRIQLENV TLLNPDPAEGPKPRPAVWL |
Function | Receptor for Slit proteins, at least for SLIT2, and seems to be involved in angiogenesis and vascular patterning. May mediate the inhibition of primary endothelial cell migration by Slit proteins. Involved in the maintenance of endothelial barrier organization and function. |
Protein Name | Roundabout Homolog 4Magic Roundabout |
Alternative Protein Names | Roundabout Homolog 4 proteinMagic Roundabout proteinROBO4 proteinUNQ421 proteinPRO3674 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance