Human RNASE7 protein (Recombinant) (N-His) (STJP005977)

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STJP005977
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human RNASE7-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: RNASE7
Gene ID: 84659
Uniprot ID: RNAS7_HUMAN
Immunogen Region: Lys31-Val155
Immunogen: Homo sapiens (Human)
Function Exhibits a potent RNase activity. Has broad-spectrum antimicrobial activity against many pathogenic microorganisms including uropathogenic E.coli (UPEC), and remarkably potent activity (lethal dose of 90% < 30 nM) against a vancomycin resistant Enterococcus faecium. Causes loss of bacterial membrane integrity. Probably contributes to urinary tract sterility. Bactericidal activity is independent of RNase activity.
Protein Name Ribonuclease 7
Rnase 7
Skin-Derived Antimicrobial Protein 2
Sap-2
Database Links Reactome: R-HSA-6803157
Cellular Localisation Secreted
Detected In Urine
Alternative Protein Names Ribonuclease 7 protein
Rnase 7 protein
Skin-Derived Antimicrobial Protein 2 protein
Sap-2 protein
RNASE7 protein
UNQ2516 protein
PRO6006 protein

Information sourced from Uniprot.org

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