Human RNASE2 protein (Recombinant) (N-His) (STJP003945)

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STJP003945
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human RNASE2-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: RNASE2
Gene ID: 6036
Uniprot ID: RNAS2_HUMAN
Immunogen Region: Lys28-Ile161
Immunogen: Homo sapiens (Human)
Post Translational Modifications A particular signal processing and glycosylation pattern may differentiate the UpI2 RNase, found specifically in pregnant women urine, from other nonsecretory RNases.
Function This is a non-secretory ribonuclease. It is a pyrimidine specific nuclease with a slight preference for U. Cytotoxin and helminthotoxin. Selectively chemotactic for dendritic cells. Possesses a wide variety of biological activities.
Protein Name Non-Secretory Ribonuclease
Eosinophil-Derived Neurotoxin
Rnase Upi-2
Ribonuclease 2
Rnase 2
Ribonuclease Us
Database Links Reactome: R-HSA-6798695
Cellular Localisation Lysosome
Cytoplasmic Granule
Matrix Of Eosinophil's Large Specific Granule
Alternative Protein Names Non-Secretory Ribonuclease protein
Eosinophil-Derived Neurotoxin protein
Rnase Upi-2 protein
Ribonuclease 2 protein
Rnase 2 protein
Ribonuclease Us protein
RNASE2 protein
EDN protein
RNS2 protein

Information sourced from Uniprot.org

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