| Function | Binds ATP, opioids and phosphatidylethanolamine. Has lower affinity for phosphatidylinositol and phosphatidylcholine. Serine protease inhibitor which inhibits thrombin, neuropsin and chymotrypsin but not trypsin, tissue type plasminogen activator and elastase. Inhibits the kinase activity of RAF1 by inhibiting its activation and by dissociating the RAF1/MEK complex and acting as a competitive inhibitor of MEK phosphorylation. HCNP may be involved in the function of the presynaptic cholinergic neurons of the central nervous system. HCNP increases the production of choline acetyltransferase but not acetylcholinesterase. Seems to be mediated by a specific receptor. |
| Protein Name | Phosphatidylethanolamine-Binding Protein 1Pebp-1HcnpppNeuropolypeptide H3Prostatic-Binding ProteinRaf Kinase Inhibitor ProteinRkip Cleaved Into - Hippocampal Cholinergic Neurostimulating PeptideHcnp |
| Database Links | Reactome: R-HSA-5674135Reactome: R-HSA-5675221Reactome: R-HSA-6802946Reactome: R-HSA-6802948Reactome: R-HSA-6802952Reactome: R-HSA-6802955Reactome: R-HSA-9649948 |
| Cellular Localisation | Cytoplasm |
| Alternative Protein Names | Phosphatidylethanolamine-Binding Protein 1 proteinPebp-1 proteinHcnppp proteinNeuropolypeptide H3 proteinProstatic-Binding Protein proteinRaf Kinase Inhibitor Protein proteinRkip Cleaved Into - Hippocampal Cholinergic Neurostimulating Peptide proteinHcnp proteinPEBP1 proteinPBP proteinPEBP protein |
Information sourced from Uniprot.org
