Human RILP protein (Recombinant) (N-His) (STJP008364)

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STJP008364
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human RILP-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: RILP
Gene ID: 83547
Uniprot ID: RILP_HUMAN
Immunogen Region: Ser21-Gln180
Immunogen: Homo sapiens (Human)
Function Rab effector playing a role in late endocytic transport to degradative compartments. Involved in the regulation of lysosomal morphology and distribution. Induces recruitment of dynein-dynactin motor complexes to Rab7A-containing late endosome and lysosome compartments. Promotes centripetal migration of phagosomes and the fusion of phagosomes with the late endosomes and lysosomes.
Protein Name Rab-Interacting Lysosomal Protein
Database Links Reactome: R-HSA-2132295
Cellular Localisation Late Endosome Membrane
Lysosome Membrane
Cytoplasmic Vesicle
Phagosome Membrane
Associated With Late Endosomal
Lysosomal And Phagosomal Membranes
The Interaction With Rab7a Is Necessary For Its Recruitment To Phagosomes
Alternative Protein Names Rab-Interacting Lysosomal Protein protein
RILP protein
PP10141 protein

Information sourced from Uniprot.org