Function | Rab effector playing a role in late endocytic transport to degradative compartments. Involved in the regulation of lysosomal morphology and distribution. Induces recruitment of dynein-dynactin motor complexes to Rab7A-containing late endosome and lysosome compartments. Promotes centripetal migration of phagosomes and the fusion of phagosomes with the late endosomes and lysosomes. |
Protein Name | Rab-Interacting Lysosomal Protein |
Database Links | Reactome: R-HSA-2132295 |
Cellular Localisation | Late Endosome MembraneLysosome MembraneCytoplasmic VesiclePhagosome MembraneAssociated With Late EndosomalLysosomal And Phagosomal MembranesThe Interaction With Rab7a Is Necessary For Its Recruitment To Phagosomes |
Alternative Protein Names | Rab-Interacting Lysosomal Protein proteinRILP proteinPP10141 protein |
Information sourced from Uniprot.org