Tissue Specificity | Ubiquitously expressed. Expressed at high level in heart and skeletal muscle. |
Post Translational Modifications | Ubiquitinated by PRKN during mitophagy, leading to its degradation and enhancement of mitophagy. Deubiquitinated by USP30. |
Function | Mitochondrial GTPase involved in mitochondrial trafficking. Probably involved in control of anterograde transport of mitochondria and their subcellular distribution. Promotes mitochondrial fission during high calcium conditions. |
Protein Name | Mitochondrial Rho Gtpase 1Miro-1Hmiro-1Rac-Gtp-Binding Protein-Like ProteinRas Homolog Gene Family Member T1 |
Database Links | Reactome: R-HSA-5689880Reactome: R-HSA-9013425 |
Cellular Localisation | Mitochondrion Outer MembraneSingle-Pass Type Iv Membrane ProteinColocalizes With Mgarp And Rhot2 At The Mitochondria |
Alternative ELISA Names | Mitochondrial Rho Gtpase 1 ELISA kitMiro-1 ELISA kitHmiro-1 ELISA kitRac-Gtp-Binding Protein-Like Protein ELISA kitRas Homolog Gene Family Member T1 ELISA kitRHOT1 ELISA kitARHT1 ELISA kit |
output | |
Information sourced from Uniprot.org