Human RGS16 protein (Recombinant) (His-Tag) (STJP016640)

Name: Human RGS16 protein (Recombinant) (His-Tag) (STJP016640)
SKU: STJP016640
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

HostE.coli

ImmunogenHuman

STJP016640

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Short Description	Recombinant-Human RGS16-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications	SDS-PAGE
Host	E.coli
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Concentration	0.5 mg/mL
Formulation	Liquid In 20mM Tris-HCl buffer (pH 8.0) containing 20% Glycerol, 0.1M NaCl
Storage Instruction	For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Gene Symbol	RGS16
Gene ID	6004
Uniprot ID	RGS16_HUMAN
Accession Number	AAH06243
Immunogen	Human
Immunogen Region	1-202aa
Immunogen Sequence	MCRTLAAFPT TCLERAKEFK TRLGIFLHKS ELGCDTGSTG KFEWGSKHSK ENRNFSEDVL GWRESFDLLL SSKNGVAAFH AFLKTEFSEE NLEFWLACEE FKKIRSATKL ASRAHQIFEE FICSEAPKEV NIDHETRELT RMNLQTATAT CFDAAQGKTR TLMEKDSYPR FLKSPAYRDL AAQASAASAT LSSCSLDEPS HT

Tissue Specificity	Abundantly expressed in retina with lower levels of expression in most other tissues.
Post Translational Modifications	Palmitoylated on Cys-2 and/or Cys-12. Phosphorylated. Phosphorylation at Tyr-168 by EGFR enhances GTPase accelerating (GAP) activity toward GNAI1.
Function	Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Plays an important role in the phototransduction cascade by regulating the lifetime and effective concentration of activated transducin alpha. May regulate extra and intracellular mitogenic signals.
Protein Name	Regulator Of G-Protein Signaling 16 Rgs16 A28-Rgs14p Retinal-Specific Rgs Rgs-R Hrgs-R Retinally Abundant Regulator Of G-Protein Signaling
Database Links	Reactome: R-HSA-416476 Reactome: R-HSA-418594 Reactome: R-HSA-418597
Cellular Localisation	Membrane Lipid-Anchor
Alternative Protein Names	Regulator Of G-Protein Signaling 16 protein Rgs16 protein A28-Rgs14p protein Retinal-Specific Rgs protein Rgs-R protein Hrgs-R protein Retinally Abundant Regulator Of G-Protein Signaling protein RGS16 protein RGSR protein

Information sourced from Uniprot.org