| Host: | E. coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human REV1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | REV1 |
| Gene ID: | 51455 |
| Uniprot ID: | REV1_HUMAN |
| Immunogen Region: | Asn472-Val652 |
| Immunogen: | Homo sapiens (Human) |
| Function | Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents. |
| Protein Name | Dna Repair Protein Rev1Alpha Integrin-Binding Protein 80Aibp80Rev1-Like Terminal Deoxycytidyl Transferase |
| Database Links | Reactome: R-HSA-110312Reactome: R-HSA-5655862Reactome: R-HSA-5656121Reactome: R-HSA-5656169 |
| Cellular Localisation | Nucleus |
| Alternative Protein Names | Dna Repair Protein Rev1 proteinAlpha Integrin-Binding Protein 80 proteinAibp80 proteinRev1-Like Terminal Deoxycytidyl Transferase proteinREV1 proteinREV1L protein |
Information sourced from Uniprot.org