Human Renin protein (Recombinant) (His-Tag) (STJP018283)

SKU:
STJP018283
£134.50 - £738.50
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Short Description :Recombinant-Human Renin-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications:SDS-PAGE/Denatured
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Concentration:1 mg/mL
Formulation:Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% Glycerol
Storage Instruction:For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol:REN
Gene ID:5972
Uniprot ID:RENI_HUMAN
Accession Number:NP_000528
Immunogen:Human
Immunogen Region:67-406aa
Immunogen Sequence:LTLGN TTSSVILTNY MDTQYYGEIG IGTPPQTFKV VFDTGSSNVW VPSSKCSRLY TACVYHKLFD ASDSSSYKHN GTELTLRYST GTVSGFLSQD IITVGGITVT QMFGEVTEMP ALPFMLAEFD GVVGMGFIEQ AIGRVTPIFD NIISQGVLKE DVFSFYYNRD SENSQSLGGQ IVLGGSDPQH YEGNFHYINL IKTGVW
Function Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney.
Protein Name Renin
Angiotensinogenase
Database Links Reactome: R-HSA-2022377
Cellular Localisation Secreted
Membrane
Associated To Membranes Via Binding To Atp6ap2
Alternative Protein Names Renin protein
Angiotensinogenase protein
REN protein

Information sourced from Uniprot.org