Human RECQL4 protein (Recombinant) (N-His) (STJP008920)

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STJP008920
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human RECQL4-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: RECQL4
Gene ID: 9401
Uniprot ID: RECQ4_HUMAN
Immunogen Region: Gly556-Pro820
Immunogen: Homo sapiens (Human)
Function An ATP-dependent DNA helicase which unwinds dsDNA with a 3'-overhang in a 3'-5' direction. Does not unwind more than 18 bp of dsDNA. May modulate chromosome segregation. The N-terminal domain (residues 1-54) binds DNA Y-shaped DNA better than ss- or dsDNA. The core helicase domain binds ssDNA.
Protein Name Atp-Dependent Dna Helicase Q4
Dna 3'-5' Helicase Recq4
Dna Helicase - Recq-Like Type 4
Recq4
Rts
Recq Protein-Like 4
Cellular Localisation Cytoplasm
Nucleus
Alternative Protein Names Atp-Dependent Dna Helicase Q4 protein
Dna 3'-5' Helicase Recq4 protein
Dna Helicase - Recq-Like Type 4 protein
Recq4 protein
Rts protein
Recq Protein-Like 4 protein
RECQL4 protein
RECQ4 protein

Information sourced from Uniprot.org