Host: | E. coli |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Recombinant-Human RECQL4-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications. |
Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Gene Symbol: | RECQL4 |
Gene ID: | 9401 |
Uniprot ID: | RECQ4_HUMAN |
Immunogen Region: | Gly556-Pro820 |
Immunogen: | Homo sapiens (Human) |
Function | An ATP-dependent DNA helicase which unwinds dsDNA with a 3'-overhang in a 3'-5' direction. Does not unwind more than 18 bp of dsDNA. May modulate chromosome segregation. The N-terminal domain (residues 1-54) binds DNA Y-shaped DNA better than ss- or dsDNA. The core helicase domain binds ssDNA. |
Protein Name | Atp-Dependent Dna Helicase Q4Dna 3'-5' Helicase Recq4Dna Helicase - Recq-Like Type 4Recq4RtsRecq Protein-Like 4 |
Cellular Localisation | CytoplasmNucleus |
Alternative Protein Names | Atp-Dependent Dna Helicase Q4 proteinDna 3'-5' Helicase Recq4 proteinDna Helicase - Recq-Like Type 4 proteinRecq4 proteinRts proteinRecq Protein-Like 4 proteinRECQL4 proteinRECQ4 protein |
Information sourced from Uniprot.org