Function | May confer resistance to the antitumor agent cisplatin. Binds to DNA and RNA. |
Protein Name | Rad52 Motif-Containing Protein 1Rad52 Homolog B |
Cellular Localisation | NucleusCytoplasmNucleolusIsoform 3 And Isoform 10 Are Predominantly Nuclear And NucleolarAfter Treatment With Proteasomal Inhibitors And Mild Heat-Shock StressIsoform 1Isoform 3Isoform 5Isoform 7Isoform 8 And Isoform 10 Are Relocalized To The Nucleolus As Dot-Like Or Irregular Subnuclear StructuresIsoform 1 Colocalized With Nuclear Promyelocytic Leukemia (Pml) And Cajal Bodies (Cb)This Association With Nuclear Bodies Is Enhanced In Response To Proteotoxic StressBut Not Isoform 1 And Isoform 5Is Relocalized In Nucleolar Caps During Transcriptional ArrestIsoform 1: CytoplasmPml BodyCajal BodyIsoform 1 Is Predominantly Cytoplasmic |
Alternative Protein Names | Rad52 Motif-Containing Protein 1 proteinRad52 Homolog B proteinRDM1 proteinRAD52B protein |
Information sourced from Uniprot.org