Human RDM1 protein (Recombinant) (N-His) (STJP008127)

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STJP008127
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human RDM1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: RDM1
Gene ID: 201299
Uniprot ID: RDM1_HUMAN
Immunogen Region: Met1-Arg232
Immunogen: Homo sapiens (Human)
Function May confer resistance to the antitumor agent cisplatin. Binds to DNA and RNA.
Protein Name Rad52 Motif-Containing Protein 1
Rad52 Homolog B
Cellular Localisation Nucleus
Cytoplasm
Nucleolus
Isoform 3 And Isoform 10 Are Predominantly Nuclear And Nucleolar
After Treatment With Proteasomal Inhibitors And Mild Heat-Shock Stress
Isoform 1
Isoform 3
Isoform 5
Isoform 7
Isoform 8 And Isoform 10 Are Relocalized To The Nucleolus As Dot-Like Or Irregular Subnuclear Structures
Isoform 1 Colocalized With Nuclear Promyelocytic Leukemia (Pml) And Cajal Bodies (Cb)
This Association With Nuclear Bodies Is Enhanced In Response To Proteotoxic Stress
But Not Isoform 1 And Isoform 5
Is Relocalized In Nucleolar Caps During Transcriptional Arrest
Isoform 1: Cytoplasm
Pml Body
Cajal Body
Isoform 1 Is Predominantly Cytoplasmic
Alternative Protein Names Rad52 Motif-Containing Protein 1 protein
Rad52 Homolog B protein
RDM1 protein
RAD52B protein

Information sourced from Uniprot.org