Human RCCD1 protein (Recombinant) (N-His) (STJP011010)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human RCCD1-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | RCCD1 |
| Gene ID | 91433 |
| Uniprot ID | RCCD1_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Met1-Ser376 |
Additional Info
| Function | Plays a role in transcriptional repression of satellite repeats, possibly by regulating H3K36 methylation levels in centromeric regions together with KDM8. Possibly together with KDM8, is involved in proper mitotic spindle organization and chromosome segregation. Plays a role in regulating alpha-tubulin deacetylation and cytoskeletal microtubule stability, thereby promoting cell migration and TGF-beta-induced epithelial to mesenchymal transition (EMT), potentially through the inhibition of KDM8. |
| Protein Name | Rcc1 Domain-Containing Protein 1 |
| Database Links | Reactome: R-HSA-9629569 |
| Cellular Localisation | ChromosomeColocalizes With Trimethylated 'Lys-9' Of Histone H3 (H3k9me3) |
| Alternative Protein Names | Rcc1 Domain-Containing Protein 1 proteinRCCD1 protein |
Information sourced from Uniprot.org