Human RBBP9 protein (Recombinant) (His-Tag) (STJP017435)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human RBBP9-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.5 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% Glycerol, 0.1M NaCl |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | RBBP9 |
| Gene ID | 10741 |
| Uniprot ID | RBBP9_HUMAN |
| Accession Number | NP_006597 |
| Immunogen | Human |
| Immunogen Region | 1-186aa |
| Immunogen Sequence |
Additional Info
| Tissue Specificity | Expressed at higher levels in tumor tissues such as carcinoma. |
| Function | Serine hydrolase (Probable). Catalyzes the hydrolytic activation of amino acid ester of the antiviral prodrug valacyclovir to its corresponding active drug, acyclovir. May negatively regulate basal or autocrine TGF-beta signaling by suppressing SMAD2-SMAD3 phosphorylation. May play a role in the transformation process due to its capacity to confer resistance to the growth-inhibitory effects of TGF-beta through interaction with RB1 and the subsequent displacement of E2F1. |
| Protein Name | Serine Hydrolase Rbbp9B5t-Overexpressed Gene ProteinProtein BogRetinoblastoma-Binding Protein 10Rbbp-10Retinoblastoma-Binding Protein 9Rbbp-9 |
| Database Links | |
| Cellular Localisation | |
| Alternative Protein Names | Serine Hydrolase Rbbp9 proteinB5t-Overexpressed Gene Protein proteinProtein Bog proteinRetinoblastoma-Binding Protein 10 proteinRbbp-10 proteinRetinoblastoma-Binding Protein 9 proteinRbbp-9 proteinRBBP9 proteinBOG proteinRBBP10 protein |
Information sourced from Uniprot.org