Tissue Specificity | Expressed in aortic endothelial cells (at protein level). |
Post Translational Modifications | |
Function | Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence of ligand, acts mainly as an activator of gene expression due to weak binding to corepressors. Required for limb bud development. In concert with RARA or RARB, required for skeletal growth, matrix homeostasis and growth plate function. |
Protein Name | Retinoic Acid Receptor GammaRar-GammaNuclear Receptor Subfamily 1 Group B Member 3 |
Database Links | Reactome: R-HSA-383280Reactome: R-HSA-5362517Reactome: R-HSA-5617472 |
Cellular Localisation | NucleusCytoplasm |
Alternative ELISA Names | Retinoic Acid Receptor Gamma ELISA kitRar-Gamma ELISA kitNuclear Receptor Subfamily 1 Group B Member 3 ELISA kitRARG ELISA kitNR1B3 ELISA kit |
output | |
Information sourced from Uniprot.org