Function | Small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form. In its active form interacts with and regulates several effectors including MAP4K4, MINK1 and TNIK. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. More generally, it is part of several signaling cascades and may regulate cytoskeletal rearrangements, cell migration, cell adhesion and cell spreading. |
Protein Name | Ras-Related Protein Rap-2aRbbp-30 |
Cellular Localisation | Recycling Endosome MembraneLipid-AnchorCytoplasmic SideMidbodyMay Also Localize To The Golgi And The Gelatinase-Containing Granules Of NeutrophilsColocalizes With Rasgef1b To Midbody At Telophase |
Alternative Protein Names | Ras-Related Protein Rap-2a proteinRbbp-30 proteinRAP2A protein |
Information sourced from Uniprot.org