Human RAP2A protein (Recombinant) (N-His) (STJP010853)

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STJP010853
€410.63 - €1,796.88
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human RAP2A-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: RAP2A
Gene ID: 5911
Uniprot ID: RAP2A_HUMAN
Immunogen Region: Met1-Gln183
Immunogen: Homo sapiens (Human)
Function Small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form. In its active form interacts with and regulates several effectors including MAP4K4, MINK1 and TNIK. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. More generally, it is part of several signaling cascades and may regulate cytoskeletal rearrangements, cell migration, cell adhesion and cell spreading.
Protein Name Ras-Related Protein Rap-2a
Rbbp-30
Cellular Localisation Recycling Endosome Membrane
Lipid-Anchor
Cytoplasmic Side
Midbody
May Also Localize To The Golgi And The Gelatinase-Containing Granules Of Neutrophils
Colocalizes With Rasgef1b To Midbody At Telophase
Alternative Protein Names Ras-Related Protein Rap-2a protein
Rbbp-30 protein
RAP2A protein

Information sourced from Uniprot.org